USCOM 1A Applications

USCOM is an exciting, non-invasive device specialized for high resolution measurement of the hemodynamic circulation.

USCOM is designed to measure normal and abnormal circulation at the level of the heart and vessels. The hemodynamic information and trending can assist the physician to guide therapies such as fluid, inotropes and vaso-active drugs. USCOM is validated from 0.12 l/min to 17 l/min and from 26 weeks gestational age to 85 years. One method for all subjects in all conditions.

USCOM has many applications across multiple clinical disciplines.
However there are a large number of emerging and very specific clinical problems where USCOM is useful.

PEDIATRICS Sepsis, resuscitation, surgery, post-surgical (cardiac and other)
ED Triage, sepsis, hypotension, hemorrhage, resuscitation, heart failure and hypertension, retrieval
ICU ICU post-surgical, post MI, heart failure, outreach/stepdown management, dialysis
ELECTROPHYSIOLOGY Optimization of pacemaker timings (AV, VV delay)
LIVER TRANSPLANTATION High blood loss surgery requires monitoring of CO
PREGNANCY Eclampsia and pre-eclampsia. Often hypertension complicates pregnancy, management of this hypertension is improved by directing therapy to stroke volume/SVR information
ANESTHESIA Pre-anesthesia assessment. Normal function is associated with an improved anesthetic outcome. Post-surgical recovery.
DRUG and DEVICE TRIALS Any trial to assess effectiveness of a drug or device should include measurement of CO, to ensure that CO remains unaffected during implantation of a device or administration of drugs (non-cardiac drugs - cancer), or to quantify the effectiveness of cardiac drugs. Because of its high sensitivity to circulatory change, USCOM can reduce the number of subjects to achieve statistical significance, thereby reducing experimental costs
HEMODIALYSIS Blood filtration is associated with a shifting fluid balance in chronic/critically ill patients so the need to optimize is crucial
BURNS Burns are associated with high levels of fluid loss which can reduce CO and frequently require fluid. USCOM can guide fluid administration and optimization
PSYCHIATRY Schizophrenics are commonly treated with Clozapine, which is associated with a relatively high incidence of cardiomyopathy resulting in reduced CO. The patients are generally recommended to have echocardiography performed every three months to exclude this complication.
HEART FAILURE CLINICS or HYPERTENSION CLINICS Hypertension and heart failure management is improved by directing therapy to SV/SVR information.
USCOM is an ethical alternative to current methods of measuring circulation in animals and is highly sensitive across the range of interventions identified in humans such as fluid resuscitation, inotropes and vaso-active therapies.
ANIMAL RESEARCH USCOM is an ethical alternative to current methods of measuring circulation in animals. The high sensitivity of the method increases the sensitivity of the studies, while reducing the cost of the studies and animal discomfort